Engerix B Vaccine

Hepatitis B Vaccine: Engerix B

Introduction

Engerix-B is an FDA-approved vaccine manufactured by GlaxoSmithKline Biologicals. It protects against infection by the hepatitis B virus (HBV), which can cause liver damage and, in severe cases, liver failure and death. The vaccine works by introducing a weakened or inactivated form of the virus into the body, prompting the immune system to produce antibodies against it.

Who Should Get the Engerix-B Vaccine?

The Centers for Disease Control and Prevention (CDC) recommends Engerix-B vaccination for:

• Infants: Three doses of Engerix-B are recommended for infants, typically given at birth, 1-2 months, and 6-18 months of age.
• Children and adolescents: Children and adolescents who have not been vaccinated as infants should receive three doses of Engerix-B. The first dose can be given as early as age 12 months, and the remaining two doses should be given at intervals of 1-2 months and 6-12 months.
• Adults: Adults who have not been vaccinated should receive three doses of Engerix-B. The doses should be given at intervals of 0, 1, and 6 months.
• People at high risk of HBV infection: Certain groups of people are at an increased risk of HBV infection and should be vaccinated. These groups include healthcare workers, people who live with someone who has HBV, people who travel to areas where HBV is common, and people who inject drugs.

How Effective is Engerix-B?

Engerix-B is a highly effective vaccine. Studies have shown that it is about 95% effective in preventing HBV infection. The vaccine's protection lasts for at least 10 years, and possibly for life.

Potential Side Effects of Engerix-B

Engerix-B is generally well-tolerated, but it can cause some side effects. The most common side effects include:

• Pain, redness, and swelling at the injection site
• Fever
• Headache
• Muscle aches
• Fatigue

These side effects are usually mild and go away within a few days. In rare cases, Engerix-B can cause more serious side effects, such as allergic reactions, seizures, and Guillain-Barré syndrome.

Contraindications and Precautions

Engerix-B should not be given to people who have had a severe allergic reaction to a previous dose of the vaccine or to any of its ingredients. It should also be used with caution in people who have a weakened immune system.

Conclusion

Engerix-B is a safe and effective vaccine that can protect against HBV infection. It is recommended for infants, children, adolescents, and adults who are at risk of infection. The vaccine is generally well-tolerated, but it can cause some mild side effects.